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Fluorescence nanotomography using resonance energy transfer: Demonstration with a protein-sugar complex

Rolinski, Olaf J. and Birch, David J.S. and McCartney, Lydia J. and Pickup, John C. (2001) Fluorescence nanotomography using resonance energy transfer: Demonstration with a protein-sugar complex. Physics in Medicine and Biology, 46 (2001). N221-N226. ISSN 0031-9155

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Abstract

A new approach to structural sensing, fluorescence resonance energy transfer nanotomography, which interprets fluorescence decay measurement in terms of site density analysis of molecular distributions, has been applied to a glucose sensor based on competitive binding with malachite green labelled dextran to the sugar binding protein concanavalinA labelled with allophycocyanin. Opportunities for structural sensing in clinical medicine are highlighted.

Item type: Article
ID code: 3059
Keywords: fluorescence nanotomography, resonance energy transfer, protein-sugar complex, nanoscience, Solid state physics. Nanoscience, Radiology Nuclear Medicine and imaging, Radiological and Ultrasound Technology
Subjects: Science > Physics > Solid state physics. Nanoscience
Department: Faculty of Science > Physics
Related URLs:
    Depositing user: Strathprints Administrator
    Date Deposited: 27 Mar 2007
    Last modified: 04 Sep 2014 10:49
    URI: http://strathprints.strath.ac.uk/id/eprint/3059

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