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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Non-negative matrix factorisation for network reordering

Lee, Clare and Higham, Desmond and Crowther, D. and Vass, J. Keith (2010) Non-negative matrix factorisation for network reordering. Monografias de la Real Academia de Ciencias de Zaragoza, 33. pp. 39-53.

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Abstract

Non-negative matrix factorisation covers a variety of algorithms that attempt to represent a given, large, data matrix as a sum of low rank matrices with a prescribed sign pattern. There are intuitave advantages to this approach, but also theoretical and computational challenges. In this exploratory paper we investigate the use of non-negative matrix factorisation algorithms as a means to reorder the nodes in a large network. This gives a set of alternatives to the more traditional approach of using the singular value decomposition. We describe and implement a range of recently proposed algorithms and evaluate their performance on synthetically constructed test data and on a real data set arising in cancer research.