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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Carotid wall motion analysis based on B-Mode Ultrasound images

Hopkins, Warren and Gao, Hao and Das, Saroj and Long, Quan (2010) Carotid wall motion analysis based on B-Mode Ultrasound images. In: IFMBE Proceedings. Springer, pp. 871-874.

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Abstract

The aim of this study was to explore the arterial wall dynamics in an attempt to demonstrate premature atherosclerosis and arterial stiffening. Methods: A dedicated motion capture (MOCAP) framework was developed based on Matlab® using a cross correlation algorithm for block matching. Results: This study demonstrated that longitudinal and radial movements decreased according to age. 60 healthy carotids were assessed using our motion tracking algorithm. The subjects were divided into three age groups; group 1: subjects younger than 35, group 2: 35 to 50, group 3: subjects over 50. A unilateral t-test was employed to assess the relationship between groups. The hypothesis test showed that wall motion in group 1 was significantly different from group 2 and group 3 (p<0.05). It was also evident that the intima-media complex demonstrated a larger longitudinal displacement than the adventitial layer. Therefore there is shear strain within the vessel wall. Conclusion: With the development of MOCAP using Matlab®, we were able to quantify and reproduce arterial wall dynamics. We aim to implement MOCAP into the routine ultrasound examination, providing a new diagnostic parameter to improve patient management. (Courtesy of SpringerLink)