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Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom : mid-season analysis 2010/11

Pebody, R. and Hardelid, P. and Fleming, D.M. and McMenamin, J. and Andrews, N. and Robertson, C. and Thomas, D. R. and SebastianPillai, P. and Ellis, J. and Carman, W. (2011) Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom : mid-season analysis 2010/11. Eurosurveillance, 16 (6). pp. 8-13. ISSN 1560-7917

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Abstract

This study provides mid-season estimates of the effectiveness of 2010/11 trivalent influenza vaccine and previous vaccination with monovalent influenza A(H1N1)2009 vaccine in preventing confirmed influenza A(H1N1)2009 infection in the United Kingdom in the 2010/11 season. The adjusted vaccine effectiveness was 34% (95% CI: -10 - 60%) if vaccinated only with monovalent vaccine in the 2009/10 season; 46% (95% CI: 7 - 69%) if vaccinated only with trivalent influenza vaccine in the 2010/11 season and 63% (95% CI: 37 - 78%) if vaccinated in both seasons.