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Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom : mid-season analysis 2010/11

Pebody, R. and Hardelid, P. and Fleming, D.M. and McMenamin, J. and Andrews, N. and Robertson, C. and Thomas, D. R. and SebastianPillai, P. and Ellis, J. and Carman, W. (2011) Effectiveness of seasonal 2010/11 and pandemic influenza A(H1N1)2009 vaccines in preventing influenza infection in the United Kingdom : mid-season analysis 2010/11. Eurosurveillance, 16 (6). pp. 8-13. ISSN 1560-7917

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Abstract

This study provides mid-season estimates of the effectiveness of 2010/11 trivalent influenza vaccine and previous vaccination with monovalent influenza A(H1N1)2009 vaccine in preventing confirmed influenza A(H1N1)2009 infection in the United Kingdom in the 2010/11 season. The adjusted vaccine effectiveness was 34% (95% CI: -10 - 60%) if vaccinated only with monovalent vaccine in the 2009/10 season; 46% (95% CI: 7 - 69%) if vaccinated only with trivalent influenza vaccine in the 2010/11 season and 63% (95% CI: 37 - 78%) if vaccinated in both seasons.

Item type: Article
ID code: 29291
Notes: Funding This work has been undertaken as part of a European Centre for Disease Control and Prevention (ECDC) funded project “I-MOVE”, which is co-ordinated by Epi-Concept (http://www.epiconcept.fr/). Conflicts of interest All authors have completed the Unified Competing Interest form at http://www.icmje.org/coi_disclosure.pdf (available on request from the corresponding author) and declare that DM Fleming has received funding to attend influenza related meetings and has received consultancy fees from influenza vaccine manufacturers who might have an interest in the submitted work in the previous 3 years. In addition, The Virus Reference Department of the Health Protection Agency receives funding from a variety of vaccine manufacturers who might have an interest in the submitted work. All other authors declare they have no conflicts of interest.
Keywords: statistics, influenza A virus, H1N1 Subtype, pandemic influenza, influenza, vaccination, Pharmacy and materia medica
Subjects: Medicine > Pharmacy and materia medica
Department: Faculty of Science > Mathematics and Statistics
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Depositing user: Pure Administrator
Date Deposited: 07 Mar 2011 23:29
Last modified: 10 Dec 2013 17:33
URI: http://strathprints.strath.ac.uk/id/eprint/29291

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