Picture of two heads

Open Access research that challenges the mind...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

Discover more...

An extracellular microelectrode array for monitoring electrogenic cells in culture

Connolly, P. and Clarke, P. and Curtis, A.S.G. and Dow, J.A.T. and Wilkinson, C.D.W. (1990) An extracellular microelectrode array for monitoring electrogenic cells in culture. Biosensors and Bioelectronics, 5 (3). pp. 223-234. ISSN 0956-5663

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

This paper describes a planar array of microelectrodes developed for monitoring the electrical activity of cells in culture. The device allows the incorporation of surface topographical features in an insulating layer above the electrodes. Semiconductor technology is employed for the fabrication of the gold electrodes and for the deposition and patterning of an insulating layer of silicon nitride. The electrodes have been tested using a cardiac cell culture of chick embryo myocytes, and the physical beating of the cultured cells correlated with the simultaneous extracellular voltage measurements obtained. It was found that extracellular stimulation of the cells was possible via the same electrodes used for recording.