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Gold nanorods for fluorescence lifetime imaging in biology

Zhang, Y. and Yu, Jun and Birch, David and Chen, Yu (2010) Gold nanorods for fluorescence lifetime imaging in biology. Journal of Biomedical Optics, 15 (2). p. 20504. ISSN 1083-3668

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Abstract

Two-photon luminescence (TPL) from gold nanorods shows considerable potential in biological imaging. We study the imaging of gold nanorods in Madin-Darby canine kidney (MDCK) cells using fluorescence lifetime imaging microscopy (FLIM). FLIM provides images with better contrast and sensitivity than intensity imaging. The characteristic fluorescence lifetime of gold nanorods is found to be less than 100 ps, which can be used to distinguish gold nanorods from other fluorescent labels and endogenous fluorophores in lifetime imaging.

Item type: Article
ID code: 26782
Keywords: two-photon luminescence, madin-darby canine kidney cells, fluorescence lifetime imaging microscopy, gold nanorods, Physics, Biomedical Engineering, Biomaterials, Electronic, Optical and Magnetic Materials, Atomic and Molecular Physics, and Optics
Subjects: Science > Physics
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Faculty of Science > Physics
Related URLs:
    Depositing user: Miss Leonie Airley
    Date Deposited: 17 Aug 2010 14:31
    Last modified: 28 Mar 2014 05:28
    URI: http://strathprints.strath.ac.uk/id/eprint/26782

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