Picture of a sphere with binary code

Making Strathclyde research discoverable to the world...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. It exposes Strathclyde's world leading Open Access research to many of the world's leading resource discovery tools, and from there onto the screens of researchers around the world.

Explore Strathclyde Open Access research content

Xanalteric acid I and II and the related phenolic compounds from endophytic Alternaria sp. isolated from mangrove plant Sonneratia alba

Kjer, J. and Wray, V. and Edrada-Ebel, R.A. and Ebel, R. and Pretsch, A. and Lin, W.H. and Proksch, P. (2009) Xanalteric acid I and II and the related phenolic compounds from endophytic Alternaria sp. isolated from mangrove plant Sonneratia alba. Journal of Natural Products, 72 (11). pp. 2053-2057. ISSN 0163-3864

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

Two new 10-oxo-10H-phenaleno[1,2,3-de]chromene-2-carboxylic acids, xanalteric acids I (1) and II (2), and 11 known secondary metabolites were obtained from extracts of the endophytic fungus Alternaria sp., isolated from the mangrove plant Sonneratia alba collected in China. The metabolites were confirmed to be of fungal origin, and the structures of the new natural products were unambiguously elucidated on the basis of extensive one- and two-dimensional NMR spectroscopic studies and mass spectrometric analysis. The two new compounds 1 and 2 exhibited weak antibiotic activity against multidrug-resistant Staphylococcus aureus. Altenusin (3) displayed broad antimicrobial activity against several additional multidrug-resistant bacterial and fungal strains.