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Executive neuropsychological functioning in individuals with Williams syndrome

Rhodes, Sinéad and Riby, D.M. and Park, J. and Fraser, E. and Campbell, L.E. (2010) Executive neuropsychological functioning in individuals with Williams syndrome. Neuropsychologia, 48 (5). pp. 1216-1226. ISSN 0028-3932

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Abstract

The present study investigated executive neuropsychological functioning in individuals with the neuro-developmental disorder Williams syndrome (WS) using a set of validated standardized neuropsychological tasks. Relatively few studies have examined frontal lobe related executive functions within the cognitive phenotype associated with the disorder. The present study compared participants with WS to typically developing participants who were individually matched for (1) chronological age and (2) verbal mental age (N= 19 each group) on tasks of attention-set shifting, planning and working memory from the Cambridge Neuropsychological Test Automated Battery (CANTAB). To address the specificity of executive function impairment, non-executive tasks of delayed short-term memory and short-term memory span were also administered. Individuals with WS (mean age 18 years) showed impaired executive functioning on tasks of attention set-shifting, working memory, and planning. Non-executive deficits were also observed in short-term delayed memory and memory span. Neuropsychological impairments were correlated with a range of behavioural problems assessed using parent-rated Questionnaires. Overall, these findings point to the role of a range of executive function impairments in WS but further suggest that cognitive impairments extend beyond executive dysfunction.

Item type: Article
ID code: 25719
Keywords: williams syndrome, executive function, working memory, delayed short-term memory, cambridge neuropsychological test automated battery, Psychology, Cognitive Neuroscience, Behavioral Neuroscience, Experimental and Cognitive Psychology
Subjects: Philosophy. Psychology. Religion > Psychology
Department: Faculty of Humanities and Social Sciences (HaSS) > School of Psychological Science and Health > Psychology
Related URLs:
    Depositing user: Miss Lisa McWhinnie
    Date Deposited: 29 Jun 2010 13:32
    Last modified: 05 Sep 2014 05:21
    URI: http://strathprints.strath.ac.uk/id/eprint/25719

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