Lizos, D.E. and Murphy, J.A. (2003) Concise synthesis of (±)-horsfiline and (±)-coerulescine by tandem cyclisation of iodoaryl alkenyl azides. Organic and Biomolecular Chemistry, 1 (1). pp. 117-122. ISSN 1477-0520
Full text not available in this repository. (Request a copy from the Strathclyde author)Official URL: http://dx.doi.org/10.1039/b208114h
Abstract
A brief, efficient and economical synthesis of the spiropyrrolidinyloxindoles, horsfiline and coerulescine, has been achieved, starting from itaconic acid and, respectively, p-anisidine or o-iodoaniline. Tandem radical cyclisation of iodoaryl alkenyl azides is the key step in both syntheses.
| Item type: | Article |
|---|---|
| ID code: | 23085 |
| Keywords: | formal total synthesis, oxindole alkaloids, spirotryprostain-B, radical cyclization, asymmetric nitroolefination, horsfiline, Chemistry |
| Subjects: | Science > Chemistry |
| Department: | Faculty of Science > Pure and Applied Chemistry |
| Related URLs: | |
| Depositing user: | Strathprints Administrator |
| Date Deposited: | 14 Jul 2010 12:07 |
| Last modified: | 12 Mar 2012 11:14 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/23085 |
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