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Dynamics of cardiac intracellular ca2+ handling: from experiments to virtual cells

Zhang, H. and Noble, D. and Cannell, M. and Orchard, C.H. and Lancaster, M. and Jones, S.A. and Boyett, M.R. and Holden, A.V. and Dempster, J. (2003) Dynamics of cardiac intracellular ca2+ handling: from experiments to virtual cells. International Journal of Bifurcation and Chaos, 13 (12). pp. 3535-3560. ISSN 0218-1274

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Abstract

Intracellular cardiac Ca2+ handling involves interactions of numerous distinct cellular and macromolecular structures. Such interactions coordinate the complicated behaviors of individual processes into spatial and temporal coherent patterns of Ca2+ sparks, oscillations and traveling waves. Understanding the dynamical behaviors and functional roles of intracellular Ca2+ handling requires not only detailed experimental information about subcellular structures and dynamics, but also useful tools to integrate and analyze this information. This requires interactions between experimental and simulation results within a virtual cell.

Item type: Article
ID code: 22547
Notes: Strathprints' policy is to record up to 8 authors per publication, plus any additional authors based at the University of Strathclyde. More authors may be listed on the official publication than appear in the Strathprints' record.
Keywords: calcium spark, oscillation, wave, Pharmacy and materia medica, Applied Mathematics, General, Engineering(all), Modelling and Simulation
Subjects: Medicine > Pharmacy and materia medica
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Strathprints Administrator
    Date Deposited: 01 Oct 2010 18:53
    Last modified: 05 Sep 2014 04:40
    URI: http://strathprints.strath.ac.uk/id/eprint/22547

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