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World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

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Simulation of deposit formation in particle laden flows: thermal properties

Mulholland, A.J. (2003) Simulation of deposit formation in particle laden flows: thermal properties. Biomedicine and Pharmacotherapy, 56 (7). p. 347. ISSN 0753-3322

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Abstract

Fatty deposits formed on arterial walls lead to atherosclerosis but it is the interplay between these deposits and the vessel walls which governs the growth of plaque formation. Cells in the vessel walls trigger the body's defenses and through a series of mechanisms lead to the promotion of plaque growth. Crucially however the vast majority of acute coronary syndromes such as, myocardial infarction, and sudden ischaemic cardiac death is caused by atherosclerotic plaque rupture and not from a stenosis growing and blocking the blood flow. Although the stress caused by the blood flow does play a role in plaque rupture, it has been found that the degree of stenosis is a relatively minor factor in predicting which plaques are most prone to rupture. In fact, atherosclerotic plaques expand into the vessel wall during much of their existence and this can make their detection problematic.