Strathprints logo
Strathprints Home | Open Access | Browse | Search | User area | Copyright | Help | Library Home | SUPrimo

The response of plasma interleukin-6 and its soluble receptors to exercise in the cold in humans

Patterson, S. and Reid, Suzanne and Gray, Stuart and Nimmo, Myra A. (2008) The response of plasma interleukin-6 and its soluble receptors to exercise in the cold in humans. Journal of Sports Sciences, 26 (9). pp. 927-933. ISSN 0264-0414

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

In this study, we wished to determine whether the changes in metabolism observed during exercise in the cold are associated with changes in interleukin-6 (IL-6) and/or its soluble receptors. Eight healthy male participants performed 1 h of cycling exercise at 70% [Vdot]O2max in a control (20°C) and cold (0°C) environment. Plasma concentrations of IL-6, soluble IL-6 receptor (sIL-6R), and sgp130 were measured before exercise, at 30 and 60 min of exercise, and 60 min after exercise. Substrate oxidation was estimated through measures of pulmonary gas exchange recorded between 50 and 55 min of cycling. Exercise in the cold resulted in an increase (P < 0.05) in carbohydrate oxidation (mean 2.58 g · min-1, s = 0.49 at 20°C vs. 2.85 g · min-1, s = 0.58 at 0°C) and a decrease (P < 0.05) in fat oxidation (0.55 g · min-1, s = 0.17 at 20°C vs. 0.38 g · min-1, s = 0.16 at 0°C) compared with the control trial. Interleukin-6 concentrations were elevated (P < 0.05) after 60 min of exercise in both the cold and control trials, with no differences between trials at any instant. Neither sIL-6R nor sgp130 was affected by exercise or the environment. The alterations in carbohydrate and fat utilization during 1 h of exercise in the cold are not paralleled by changes in plasma concentrations of IL-6 or its soluble receptors.

Item type: Article
ID code: 19614
Keywords: carbohydrate, cold environment, exercise, fat, interleukin-6, Sports Medicine, Personal health and hygiene, including exercise, nutrition , Physiology, Orthopedics and Sports Medicine, Physical Therapy, Sports Therapy and Rehabilitation
Subjects: Medicine > Internal medicine > Sports Medicine
Medicine > Public aspects of medicine > Personal health and hygiene, including exercise, nutrition
Science > Physiology
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Strathprints Administrator
    Date Deposited: 27 May 2010 10:09
    Last modified: 05 Sep 2014 01:57
    URI: http://strathprints.strath.ac.uk/id/eprint/19614

    Actions (login required)

    View Item