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Feruhermonins a-c: three daucane esters from the seeds of ferula hermonis (apiaceae)

Auzi, A.A. and Gray, A.I. and Salem, M.M. and Badwan, A.A. and Sarker, S.D. (2008) Feruhermonins a-c: three daucane esters from the seeds of ferula hermonis (apiaceae). Journal of Asian Natural Products Research, 10 (8). pp. 701-707. ISSN 1028-6020

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Abstract

Seventeen daucane esters have been isolated from the seeds of Ferula hermonis Boiss (Apiaceae). Three of these sesquiterpenes, 4 beta-hydroxy-6 alpha- benzoyl-7-daucen-9-one (1), 4 beta, 8 beta-dihydroxy-6 alpha-benzoyl-dauc-9-ene (2), and 4 beta, 9 alpha-dihydroxy-6 alpha-benzoyl-dauc-7-ene (4), named feruhermonins A-C, respectively, are novel natural products. The structures of these compounds were elucidated unequivocally by a series of 1D and 2D NMR analyses. Although 4 beta, 8 beta-dihydroxy-6 alpha-(4-hydroxy-3-methoxybenzoyl)-dauc-9-ene (3) was reported previously, the complete spectroscopic data for this compound are presented here for the first time.

Item type: Article
ID code: 19557
Keywords: ferula hermonis, seeds, apiaceae, daucane esters, sesquiterpene, Pharmacy and materia medica, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Complementary and alternative medicine, Analytical Chemistry, Pharmacology
Subjects: Medicine > Pharmacy and materia medica
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Faculty of Engineering > Civil and Environmental Engineering
Related URLs:
    Depositing user: Strathprints Administrator
    Date Deposited: 31 May 2010 13:50
    Last modified: 05 Sep 2014 01:46
    URI: http://strathprints.strath.ac.uk/id/eprint/19557

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