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Is there a role for P2 receptors other than the P2X1 subtype in parasympathetic cotransmission in the urinary bladder?

Kennedy, C. (2008) Is there a role for P2 receptors other than the P2X1 subtype in parasympathetic cotransmission in the urinary bladder? Purinergic Signalling, 4. S200-S200. ISSN 1573-9538

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Abstract

Parasympathetic nerves innervate the detrusor muscle of the urinary bladder, but a non-cholinergic component ofneurotransmission was recognised over 100 years ago (Langley & Anderson, 1895). Subsequently, ATP was identified asthe cotransmitter with acetylcholine (Kasakov & Burnstock, 1983). Here we have determined the effects of P2X receptorantagonists on the non-cholinergic component of neurotransmission.

Item type: Article
ID code: 19501
Keywords: P2 receptors, P2X1 subtype, parasympathetic, cotransmission, urinary bladder, acetylcholine, Pharmacy and materia medica, Therapeutics. Pharmacology, Cellular and Molecular Neuroscience, Cell Biology, Molecular Biology
Subjects: Medicine > Pharmacy and materia medica
Medicine > Therapeutics. Pharmacology
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Depositing user: Strathprints Administrator
Date Deposited: 18 May 2010 15:45
Last modified: 21 May 2015 11:46
Related URLs:
URI: http://strathprints.strath.ac.uk/id/eprint/19501

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