Picture of scraped petri dish

Scrape below the surface of Strathprints...

Explore world class Open Access research by researchers at the University of Strathclyde, a leading technological university.

Explore

Is there a role for P2 receptors other than the P2X1 subtype in parasympathetic cotransmission in the urinary bladder?

Kennedy, C. (2008) Is there a role for P2 receptors other than the P2X1 subtype in parasympathetic cotransmission in the urinary bladder? Purinergic Signalling, 4. S200-S200. ISSN 1573-9538

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

Parasympathetic nerves innervate the detrusor muscle of the urinary bladder, but a non-cholinergic component ofneurotransmission was recognised over 100 years ago (Langley & Anderson, 1895). Subsequently, ATP was identified asthe cotransmitter with acetylcholine (Kasakov & Burnstock, 1983). Here we have determined the effects of P2X receptorantagonists on the non-cholinergic component of neurotransmission.