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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Thermal investigation into the interaction of cetostearyl alcohol and a cetostearyl alcohol/sodium lauryl sulphate mixed emulsifier with liquid paraffin

Rouse, J.J. and Kim, J.H. and Lawrence, M.J. and Eccleston, G.M. (2008) Thermal investigation into the interaction of cetostearyl alcohol and a cetostearyl alcohol/sodium lauryl sulphate mixed emulsifier with liquid paraffin. Journal of Pharmacy and Pharmacology, 60 (S1). A61-A61. ISSN 0022-3573

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Abstract

In previous work, mobile nanoemulsions were prepared by the ultrasonication of liquid paraffin (LP) in water macroemulsions containing the mixed emulsifier (ME) sodium lauryl sulphate (SLS) and cetostearyl alcohol (CSA; Kim et al 2007). It was shown that the lamellar gel networks, formed when the ME interacts with water (ternary system), were not present in freshly prepared nanoemulsions. In these systems, the endotherm associated with the lamellar phase was absent and replaced by a prominent, broad unidentified endotherm between 50 and 60C. The aim of this work was to identify the nature of this endotherm to gain a better understanding of nanoemulsion microstructure. To this end, the interactions of the ME and its components in oil were investigated.