Mammen, A. and Farraye, F.A. and Liang, Y. and Harnett, W. and Shin, H. and Harnett, M.M. and Nikolajczyk, B. and Ganley-Leal, L. (2008) The interplay between human b cells, eosinophils and helminths: a novel aspect of the hygiene hypothesis. American Journal of Tropical Medicine and Hygiene, 79 (6). pp. 337-338. ISSN 0002-9637
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
The hygiene hypothesis is based on the premise that lack of exposure to helminths predisposes certain individuals to immune-mediated disease, such as inflammatory bowel disease (IBD). This hypothesis is supported by epidemiological data that shows developed countries with a low prevalence of helminth infections have higher incidence of allergic and inflammatory diseases. Helminths modulate the host immune response in a manner that dampens the exaggerated response to innocuous antigens, such as commensal bacteria.
| Item type: | Article |
|---|---|
| ID code: | 19349 |
| Keywords: | human b cells, eosinophils, helminth, hygiene hypothesis, immune-mediated disease, inflammatory bowel disease, Immunology |
| Subjects: | Science > Microbiology > Immunology |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Strathprints Administrator |
| Date Deposited: | 02 Jun 2010 10:13 |
| Last modified: | 12 Mar 2012 11:12 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/19349 |
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