Benson, R.A. and Hutchison, S. and Millington, O.R. and McInnes, I.B. and Garside, P. and Brewer, J.M. (2008) Plasmacytoid dendritic cells and antigen presentation to CD4+t cells. Immunology, 125 (s1). p. 102. ISSN 0019-2805
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
The enigmatic antigen presenting role of plasmacytoid dendritic cells (pDCs) has generated considerable interest in recent years. More recently,their interactions with CD4+ T cells and subsequent regulation of pathology in models of autoimmune disease have made them interesting targets for biological intervention. Our studies in a novel murine model of rheumatoid arthritis (RA), demonstrate that pDCs act to limit the spontaneous induction of auto-reactive T cell responses and autoantibody production and can limit the severity of pathology.
| Item type: | Article |
|---|---|
| ID code: | 19303 |
| Keywords: | plasmacytoid dendritic cells, antigen presentation, CD4+t cells, immunology, Immunology, Pharmacy and materia medica, Biology |
| Subjects: | Science > Microbiology > Immunology Medicine > Pharmacy and materia medica Science > Natural history > Biology |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Faculty of Science > Centre for Biophotonics |
| Related URLs: | |
| Depositing user: | Strathprints Administrator |
| Date Deposited: | 18 May 2010 15:16 |
| Last modified: | 04 Oct 2012 13:07 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/19303 |
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