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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

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Real time in vivo behaviour of CD4(+) T cells from naive, primed and orally tolerised mice during secondary antigen exposure

Rush, C.M. and Bryson, K.J. and Hutchison, S. and Garside, P. and Brewer, J.M. (2008) Real time in vivo behaviour of CD4(+) T cells from naive, primed and orally tolerised mice during secondary antigen exposure. Immunology, 125 (s1). p. 76. ISSN 0019-2805

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Abstract

Previous studies investigating T cell dynamics and interactions have revealed subtle differences in the clustering behaviour of CD4+ T cells during the induction of immunological tolerance and priming in real time, in intact lymph nodes. However, the behaviour of primed and tolerised CD4+ T cells upon subsequent antigen challenge remains unclear.