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Real time in vivo behaviour of CD4(+) T cells from naive, primed and orally tolerised mice during secondary antigen exposure

Rush, C.M. and Bryson, K.J. and Hutchison, S. and Garside, P. and Brewer, J.M. (2008) Real time in vivo behaviour of CD4(+) T cells from naive, primed and orally tolerised mice during secondary antigen exposure. Immunology, 125 (s1). p. 76. ISSN 0019-2805

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Abstract

Previous studies investigating T cell dynamics and interactions have revealed subtle differences in the clustering behaviour of CD4+ T cells during the induction of immunological tolerance and priming in real time, in intact lymph nodes. However, the behaviour of primed and tolerised CD4+ T cells upon subsequent antigen challenge remains unclear.