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Cardiac troponin T as an adverse prognostic biomarker in established renal failure

Grieve, A. and Ansari, A. and Smith, G. and Smith, W. (2009) Cardiac troponin T as an adverse prognostic biomarker in established renal failure. Scottish Medical Journal, 54 (3). p. 53. ISSN 0036-9330

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Abstract

Troponin (Tn) proteins are the gold standard of biomarkers in myocardial injury. Both TnT and TnI are sensitive and specific in reflecting myocardial damage; however they do not indicate the mechanism of injury. Troponins can be altered in non-cardiac conditions. Many hypotheses have been put forward for the elevation of troponins in dialysis patients; but how do we interpret the results? This study measured TnT in our haemodialysis population and outcome (mortality) was audited over 36 months.