The role of lyophilisation in the enhancement of glibenclamide release from hard gelatin capsules

Mansour, H. and McInnes, F.J. and Florence, A.J. and Mullen, A. (2009) The role of lyophilisation in the enhancement of glibenclamide release from hard gelatin capsules. Journal of Pharmacy and Pharmacology, 61 (S1). A38-A39. ISSN 0022-3573 (https://doi.org/10.1211/002235709789036991)

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Abstract

The aim of this study was to enhance the release rate of the hypoglycaemic agent glibenclamide from hard gelatin capsules through co-lyophilisation with sodium lauryl sulphate (SLS) and perform physical characterisation of the lyophilised product.