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Preparation of polymeric microspheres as an ophthalmic drug delivery system for brimonidine tartrate

Couston, R. and McBride, E. and Wilson, C.G. (2009) Preparation of polymeric microspheres as an ophthalmic drug delivery system for brimonidine tartrate. Journal of Pharmacy and Pharmacology, 61 (S1). A22-A23. ISSN 0022-3573

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Abstract

A dramatic increase in the incidence of eye diseases, such as age-related macular degeneration, and inadequate therapeutic control has led to the search for advanced methods of sustained and targeted drug delivery. The development of polymeric devices, matrix implants and microspheres has facilitated the prolonged controlled release of therapies to the target sites. The aim of this study is to prepare brimonidine tartrate-loaded microspheres, which possess suitable characteristics for development into an implantable device that will later exploit the binding properties of ocular melanin to influence the release properties.

Item type: Article
ID code: 18960
Keywords: polymeric microspheres, ophthalmic drug delivery system, brimonidine tartrate, Pharmacy and materia medica, Therapeutics. Pharmacology, Pharmaceutical Science, Pharmacology
Subjects: Medicine > Pharmacy and materia medica
Medicine > Therapeutics. Pharmacology
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Strathprints Administrator
    Date Deposited: 22 Jun 2010 11:16
    Last modified: 05 Sep 2014 02:55
    URI: http://strathprints.strath.ac.uk/id/eprint/18960

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