Strathprints Home | Open Access | Browse | Search | User area | Copyright | Help | Library Home | SUPrimo

Spatial aspects of signalling by sphingosine 1-phosphate

Pyne, S. and Lee, S.C. and Long, J. and Gillies, L. and Pyne, N.J. (2009) Spatial aspects of signalling by sphingosine 1-phosphate. [Proceedings Paper]

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

Sphingosine kinase (SK) catalyses the phosphorylation of sphingosine to produce sphingosine 1-phosphate (S1P). S1P is a bioactive lipid that regulates cell proliferation, survival, migration etc. Extracellular S1P mediates its effects by binding to a family of five closely related G protein coupled receptors, S1P1-5. In addition, intracellular S1P may bind to undefined intracellular targets to elicit cellular responses. The focus of our recent work has

Item type: Proceedings Paper
ID code: 18951
Keywords: spatial aspect, s signalling, sphingosine 1-phosphate, Therapeutics. Pharmacology
Subjects: Medicine > Therapeutics. Pharmacology
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Strathprints Administrator
    Date Deposited: 22 Jun 2010 09:55
    Last modified: 17 Jul 2013 01:23
    URI: http://strathprints.strath.ac.uk/id/eprint/18951

    Actions (login required)

    View Item