Mayer, G. and Lohberger, A. and Butzen, S. and Pofahl, M. and Blind, M. and Heckel, A. (2009) From selection to caged aptamers: identification of light-dependent ssdna aptamers targeting cytohesin. Bioorganic and Medicinal Chemistry Letters, 19 (23). pp. 6561-6564.
Full text not available in this repository. (Request a copy from the Strathclyde author)Official URL: http://dx.doi.org/10.1016/j.bmcl.2009.10.032
Abstract
Caged aptamers represent valuable tools for the spatiotemporal control of protein function by light. Here we describe a general route starting with the de novo selection process targeting cytohesin-1 and aiming at the synthesis of caged aptamers without the prior knowledge of detailed structural determinants of aptamer-target binding.
| Item type: | Article |
|---|---|
| ID code: | 18897 |
| Keywords: | nucleic acids, aptamers, caged compounds, Pharmacy and materia medica |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Strathprints Administrator |
| Date Deposited: | 20 May 2010 15:55 |
| Last modified: | 04 Oct 2012 13:14 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/18897 |
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