Strathprints Home | Open Access | Browse | Search | User area | Copyright | Help | Library Home | SUPrimo

Toxins affecting k+ channels

Rowan, E.G. and Harvey, A.L. (1996) Toxins affecting k+ channels. Brazilian Journal of Medical and Biological Research, 29 (12). pp. 1765-1780. ISSN 0100-879X

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

Potassium channels are involved in modulating the excitability of neurones by regulating the membrane potential, or by affecting the amount of neurotransmitter released from nerve terminals. Potassium channels are highly diverse and can be activated by either voltage or increased intracellular calcium concentration. The potassium channel forms a highly selective membrane pore. Four subunits each with six membrane-spanning regions (S1-S6) are required to produce a functional pore. Molecular biologists have cloned more than 50 different potassium channel subtypes. Naturally occurring protein toxins have been used to pharmacologically characterize native and cloned potassium channels.

Item type: Article
ID code: 18350
Keywords: voltage-dependent potassium channels, calcium-dependent potassium channels, potassium channel toxins, neuropharmacology, molecular pharmacology, Pharmacy and materia medica, Biochemistry, Neuroscience(all), Cell Biology, Immunology, Pharmacology, Toxicology and Pharmaceutics(all), Biophysics, Physiology, Medicine(all)
Subjects: Medicine > Pharmacy and materia medica
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
Depositing user: Strathprints Administrator
Date Deposited: 25 Mar 2010 18:19
Last modified: 05 Sep 2014 00:55
URI: http://strathprints.strath.ac.uk/id/eprint/18350

Actions (login required)

View Item