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World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

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Melphalan and urinary estrogens

Anderson, J.M. and Grant, J.K. and Gettinby, G. (1979) Melphalan and urinary estrogens. British Journal of Cancer, 40 (2). pp. 314-315. ISSN 1532-1827

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Abstract

A test of the concept of chemical suppression of ovarian function by cytotoxic drugs previously reported (Anderson et al., 1978, Br. J. Cancer, 37, 477) revealed no supportive evidence from follicular and luteal-phase measurements of plasma oestradiol (E2) in 6 premenopausal women prescribed repeated 5-day courses of melphalan after mastectomy for cancer. To circumvent the difficulties of frequent repeated blood sampling, 3 of these patients were studied in greater depth.