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Encephalitis in mice with congenital ocular toxoplasmosis

Graham, D.I. and Hay, J. and Hutchison, W.M. and Siim, J.C. (1984) Encephalitis in mice with congenital ocular toxoplasmosis. Journal of Pathology, 142 (4). pp. 265-277. ISSN 0022-3417

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Abstract

The brains of mice with congenital ocular toxoplasmosis were examined histologically. Toxoplasma tissue cysts and a subacute/chronic meningo-encephalitis were present in the brains of all infected mice. The findings were very similar to those seen in human congenital toxoplasmosis. The murine model of congenital toxoplasmic encephalitis described in this paper will be valuable in the study of the pathogenesis, natural history and treatment of this condition.

Item type: Article
ID code: 17818
Notes: No contact email found.
Keywords: toxoplasmosis, congenital infection, encephalitis, ocular disease, mice, Pharmacy and materia medica, Pathology and Forensic Medicine
Subjects: Medicine > Pharmacy and materia medica
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Strathprints Administrator
    Date Deposited: 07 May 2010 14:29
    Last modified: 05 Sep 2014 00:27
    URI: http://strathprints.strath.ac.uk/id/eprint/17818

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