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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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Encephalitis in mice with congenital ocular toxoplasmosis

Graham, D.I. and Hay, J. and Hutchison, W.M. and Siim, J.C. (1984) Encephalitis in mice with congenital ocular toxoplasmosis. Journal of Pathology, 142 (4). pp. 265-277. ISSN 0022-3417

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The brains of mice with congenital ocular toxoplasmosis were examined histologically. Toxoplasma tissue cysts and a subacute/chronic meningo-encephalitis were present in the brains of all infected mice. The findings were very similar to those seen in human congenital toxoplasmosis. The murine model of congenital toxoplasmic encephalitis described in this paper will be valuable in the study of the pathogenesis, natural history and treatment of this condition.