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Pretreatment with beta-blockers and the frequency of hypokalemia in patients with acute chest pain

Simpson, E. and Rodger, J.C. and Raj, S.M. and Wong, C. and Wilkie, L. and Robertson, C. (1987) Pretreatment with beta-blockers and the frequency of hypokalemia in patients with acute chest pain. British Heart Journal, 58 (5). pp. 499-504. ISSN 0007-0769

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    Abstract

    Plasma potassium concentration was measured at admission in 1234 patients who presented with acute chest pain. One hundred and ninety five patients were on P blockers before admission. The potassium concentrations of patients admitted early (within four hours of onset of symptoms) were compared with those admitted later (4-18 hours after onset of symptoms). There was a transient fall in plasma potassium concentrations in patients not pre-treated with ,B blockers. This was not seen in patients who had been on P blockers before admission. Nonselective ,B blockers were more effective than cardioselective agents in maintaining concentrations of plasma potassium. These findings suggest a mechanism for the beneficial effects of ,B blockers on morbidity and mortality in acute myocardial infarction.

    Item type: Article
    ID code: 17774
    Keywords: beta-blockers, hypokalemia, acute chest pain, Medicine (General), Probabilities. Mathematical statistics
    Subjects: Medicine > Medicine (General)
    Science > Mathematics > Probabilities. Mathematical statistics
    Department: Faculty of Science > Mathematics and Statistics
    Faculty of Humanities and Social Sciences (HaSS) > School of Psychological Science and Health > Psychology
    Related URLs:
      Depositing user: Strathprints Administrator
      Date Deposited: 11 May 2010 14:17
      Last modified: 11 Dec 2013 14:38
      URI: http://strathprints.strath.ac.uk/id/eprint/17774

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