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Effect of sustained release and pulse release anthelmintic intraruminal devices on development of pathophysiological changes and parasite populations in calves infected with Ostertagia ostertagi and Cooperia oncophora

Holmes, P.H. and Bairden, K. and McKechnie, D. and Gettinby, G. and McWilliam, P.N. (1991) Effect of sustained release and pulse release anthelmintic intraruminal devices on development of pathophysiological changes and parasite populations in calves infected with Ostertagia ostertagi and Cooperia oncophora. Research in Veterinary Science, 51 (2). pp. 223-226. ISSN 0034-5288

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Abstract

An experiment was conducted in calves to investigate the effect of sustained release and pulse release anthelmintic intraruminal boli on the development of pathophysiological changes following daily infection with Ostertagia ostertagi and Cooperia oncophora for six weeks. After infection various pathophysiological changes were detected including increases in serum pepsinogen concentration, enteric plasma protein losses and in the catabolic rate of albumin. Such changes developed rapidly in the unprotected calves following patency after 17 days and persisted until the termination of the study. There were indications that the sustained anthelmintic release device was more efficacious than the pulse anthelmintic release device in reducing the worm burdens and early pathophysiological changes associated with infection. It was found at necropsy that the release of anthelmintic by the oxfendazole pulse release bolus had been delayed in several calves.

Item type: Article
ID code: 17730
Keywords: parasitism, calves, anthelmintic intraruminal boli, Ostertagia ostertagi, Cooperia oncophora, Probabilities. Mathematical statistics, Zoology, Microbiology, veterinary(all)
Subjects: Science > Mathematics > Probabilities. Mathematical statistics
Science > Zoology
Science > Microbiology
Department: Faculty of Science > Mathematics and Statistics
Related URLs:
    Depositing user: Strathprints Administrator
    Date Deposited: 12 May 2010 17:22
    Last modified: 05 Sep 2014 00:39
    URI: http://strathprints.strath.ac.uk/id/eprint/17730

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