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Imidazole catalyzed silica synthesis: Progress toward understanding the role of histidine in (bio)silicification

Patwardhan, Siddharth V (2009) Imidazole catalyzed silica synthesis: Progress toward understanding the role of histidine in (bio)silicification. Journal of Materials Research, 24 (4). pp. 1700-1708. ISSN 0884-2914

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Abstract

Histidine is an amino acid present in proteins involved in biosilica formation and often found in peptides identified during phage display studies but its role(s) and the extent of its involvement in the silica precipitation process is not fully understood. In this contribution we describe results from an in vitro silicification study conducted using poly-histidine (P-His) and a series of different molecular weight synthetic polymers containing the imidazole functionality (polyvinyl imidazole, PVI) for comparison. We show that the presence of imidazole from PVI or P-His is able to catalyze silicic acid condensation; the effect being greater for P-His. The catalytic mechanism is proposed to involve the dual features of the imidazole group-its ability to form hydrogen bonds with silicic acid and electrostatic attraction toward oligomeric silicic acid species.

Item type: Article
ID code: 16863
Keywords: imidazole catalyzed silica synthesis, histidine, (bio)silicification, Science (General), Chemical engineering, Mechanics of Materials, Materials Science(all), Mechanical Engineering, Condensed Matter Physics
Subjects: Science > Science (General)
Technology > Chemical engineering
Department: Faculty of Engineering > Chemical and Process Engineering
Related URLs:
    Depositing user: Mrs Marie Henderson
    Date Deposited: 19 Mar 2010 19:57
    Last modified: 05 Sep 2014 03:03
    URI: http://strathprints.strath.ac.uk/id/eprint/16863

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