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Supercritical fluid chromatography in forensic science: a critical appraisal

McAvoy, Y. and Backstrom, B. and Janhunen, K. and Stewart, A. and Cole, M.D. (1999) Supercritical fluid chromatography in forensic science: a critical appraisal. Forensic Science International, 99 (2). pp. 107-122. ISSN 0379-0738

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The application of supercritical fluid chromatography (SFC) in forensic science is reviewed. The applications centre on the analysis of explosives and of drugs of abuse. The systems employed are discussed in the context of comparison with gas chromatography and high-performance liquid chromatography methods which are traditionally used for such analyses. The advantages and disadvantages of SFC over these methods are discussed. Recommendations are made for the developments which are required in SFC technology if it is to find greater application in forensic science.