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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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Intracavity absorption spectrometry: a new technique for process analysis?

Elejalde, U. and Wright, A.J. and Girkin, J.M. (2008) Intracavity absorption spectrometry: a new technique for process analysis? Chimca Oggi, 26 (1). pp. 12-13. ISSN 0392-839X

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Abstract

We have investigated the application of narrow-band intracavity spectroscopy for high throughput characterization and detection of reaction products in-situ. An external cavity diode laser (ECDL), wavelength tunable from 810-890 nm, was used to measure varying concentrations of a range of compounds in solution. A linear calibration curve for parts per billion (ppb) concentrations corresponding to 17nM has been recorded. By replacing the grating with a high reflective mirror, parts per trillion (ppt) concentration detection was also achieved corresponding to 340pM. We believe that this technique provides a method for fast and safe measurements of reactions in real time and has potential applications in the pharmaceutical and chemical industry as well as for integrated bio-diagnostics lab-on-a-chip devices.