Picture of person typing on laptop with programming code visible on the laptop screen

World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

Explore

Differential effect of substrate stiffness and adsorbed fibronectin density on vascular smooth muscle migration rate

Whitton, A. and Flint, D.J. and Black, R.A. (2009) Differential effect of substrate stiffness and adsorbed fibronectin density on vascular smooth muscle migration rate. European Cells and Materials, 18 (Suppl.). p. 29. ISSN 1473-2262

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

Current surgical approaches to the treatment of patients with cardiovascular disease include the implantation of devices that aim to restore and maintain the flow of blood; however, the patency of such devices in the long term is limited by a physiological process called intimal hyperplasia (IH) or restenosis: the thickening of the vessel wall in response to injury.http://www.ecmjournal.orgThis study aims to investigate the effect of both the stiffness of the implanted material and the concentration of adsorbed proteins from the blood onto the material surface on the migration of the cells resident in the vessel wall; an important early stage in the progression of IH.