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Structural instability in an autophosphorylating kinase switch

Grinfeld, M. and Webb, S.D. (2009) Structural instability in an autophosphorylating kinase switch. Mathematical Biosciences, 219 (2). pp. 92-96. ISSN 0025-5564

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    Abstract

    We analyse a simple kinase model that exhibits bistability when there is no protein turnover, and show analytically that the property of being bistable is not necessarily conserved when degradation and synthesis of the kinase are taken into account.

    Item type: Article
    ID code: 13399
    Keywords: bistability, protein turnover, structural instability, numerical mathematics, statistics, Probabilities. Mathematical statistics, Mathematics
    Subjects: Science > Mathematics > Probabilities. Mathematical statistics
    Science > Mathematics
    Department: Faculty of Science > Mathematics and Statistics
    Related URLs:
      Depositing user: Mrs Carolynne Westwood
      Date Deposited: 12 Nov 2009 15:03
      Last modified: 11 Oct 2012 22:56
      URI: http://strathprints.strath.ac.uk/id/eprint/13399

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