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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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Structural instability in an autophosphorylating kinase switch

Grinfeld, M. and Webb, S.D. (2009) Structural instability in an autophosphorylating kinase switch. Mathematical Biosciences, 219 (2). pp. 92-96. ISSN 0025-5564

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Abstract

We analyse a simple kinase model that exhibits bistability when there is no protein turnover, and show analytically that the property of being bistable is not necessarily conserved when degradation and synthesis of the kinase are taken into account.