Strathprints logo
Strathprints Home | Open Access | Browse | Search | User area | Copyright | Help | Library Home | SUPrimo

Structural instability in an autophosphorylating kinase switch

Grinfeld, M. and Webb, S.D. (2009) Structural instability in an autophosphorylating kinase switch. Mathematical Biosciences, 219 (2). pp. 92-96. ISSN 0025-5564

[img]
Preview
PDF (strathprints013399.pdf)
strathprints013399.pdf

Download (276kB) | Preview

Abstract

We analyse a simple kinase model that exhibits bistability when there is no protein turnover, and show analytically that the property of being bistable is not necessarily conserved when degradation and synthesis of the kinase are taken into account.

Item type: Article
ID code: 13399
Keywords: bistability, protein turnover, structural instability, numerical mathematics, statistics, Probabilities. Mathematical statistics, Mathematics, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Modelling and Simulation, Applied Mathematics, Statistics and Probability, Immunology and Microbiology(all), Medicine(all)
Subjects: Science > Mathematics > Probabilities. Mathematical statistics
Science > Mathematics
Department: Faculty of Science > Mathematics and Statistics
Depositing user: Mrs Carolynne Westwood
Date Deposited: 12 Nov 2009 15:03
Last modified: 15 Apr 2015 09:24
URI: http://strathprints.strath.ac.uk/id/eprint/13399

Actions (login required)

View Item View Item