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Discover Open Access research at Strathprints

It's International Open Access Week, 24-30 October 2016. This year's theme is "Open in Action" and is all about taking meaningful steps towards opening up research and scholarship. The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Explore recent world leading Open Access research content by University of Strathclyde researchers and see how Strathclyde researchers are committing to putting "Open in Action".


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Imaging T-cell movement in the brain during experimental cerebral malaria

Ortolano, F. and Maffia, Pasquale and Dever, G. and Hutchison, S. and Benson, R. and Millington, O.R. and De Simoni, M.G. and Bushell, T. and Garside, P. and Carswell, H.V. and Brewer, J.M. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31 (3). pp. 147-150. ISSN 0141-9838

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T-cells are known to play a role in the pathology associated with experimental cerebral malaria, although it has not previously been possible to examine their behaviour in brain. Using multiphoton laser scanning microscopy, we have examined the migration and movement of these cells in brain tissue. We believe that this approach will help define host-parasite interactions and examine how intervening in these relationships affects the development of cerebral pathology.