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Dihydrostilbene derivatives from the Mongolian medicinal plant Scorzonera radiata

Wang, Yao and Edrada-Ebel, RuAngelie and Tsevegsurent, Nanzad and Sendker, Jandirk and Braun, Manfred and Wray, Victor and Lin, Wenhan and Proksch, Peter (2009) Dihydrostilbene derivatives from the Mongolian medicinal plant Scorzonera radiata. Journal of Natural Products, 72 (4). pp. 671-675. ISSN 0163-3864

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Abstract

Chromatographic separation of a crude extract obtained from aerial parts of the Mongolian medicinal plant Scorzonera radiata yielded five new dihydrostilbenes, scorzodihydrostilbenes A−E (1−5). The structures were unambiguously elucidated on the basis of one- and two-dimensional NMR (1H, 13C, COSY, HMBC, HMQC, and ROESY) and mass spectrometric data. Compounds 1−5 exhibited antioxidative activity when analyzed in the DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. For 1 and 5 the antioxidant activities were stronger than that of the well-known naturally occurring stilbene antioxidant resveratrol.

Item type: Article
ID code: 13258
Keywords: dihydrostilbene derivatives, mongolian medicinal plant, drugs, pharmacology, scorzonera radiata, Therapeutics. Pharmacology, Pharmacy and materia medica, Microbiology
Subjects: Medicine > Therapeutics. Pharmacology
Medicine > Pharmacy and materia medica
Science > Microbiology
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Ms Ann Barker-Myles
    Date Deposited: 13 Oct 2009 15:36
    Last modified: 12 Mar 2012 10:56
    URI: http://strathprints.strath.ac.uk/id/eprint/13258

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