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Antibacterial and antifungal activities of the constituents of flemingia paniculata

Rahman, M. Mukhlesur and Gray, Alexander I. and Khondkar, Proma and Sarker, Satyajit D. (2008) Antibacterial and antifungal activities of the constituents of flemingia paniculata. Pharmaceutical Biology, 46 (5). pp. 356-359. ISSN 1388-0209

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Abstract

A salicylic acid derivative (1), a cinnamaldehyde (2), and six isoflavones (3-8) from the stem bark of Flemingia paniculata. Wall. (Leguminosae) were tested for antibacterial (both Gram-positive and Gram-negative) and antifungal activities. All the compounds showed significant activities against the test organisms having MIC values in the range of 1.57-200 μ g/mL. The highest potency (MIC = 1.57 μ g/mL) was exhibited by 3 against Staphylococcus aureus.