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Open Access research that challenges the mind...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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Mapping the interactions among biomaterials, adsorbed proteins, and human embryonic stem cells

Mei, Ying and Gerecht, Sharon and Taylor, Michael and Urquhart, Andrew J. and Bogatyrev, Said R. and Cho, Seung-Woo and Davies, Martyn C. and Alexander, Morgan R. and Langer, Robert S. and Anderson, Daniel G. (2009) Mapping the interactions among biomaterials, adsorbed proteins, and human embryonic stem cells. Advanced Materials, 21 (27). pp. 2781-2786. ISSN 1521-4095

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Abstract

An integrated high-throughput polymer synthesis and rapid material/protein/cell interaction assays were developed to optimize stem cell microenvironments. Microarrayed polymers were synthesized and studied for the ability to support the growth of partially differentiated human embryonic stem cells. In parallel, a programmed laser scanning cytometry system was developed to allow for rapid quantification of cell material interaction.