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Sex hormones and modulation of immunity against leishmaniasis

Snider, Heidi and Lezama-Davila, Claudio and Alexander, J. and Satoskar, Abhay R. (2009) Sex hormones and modulation of immunity against leishmaniasis. Neuroimmunomodulation, 16 (2). pp. 106-113. ISSN 1021-7401

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Abstract

Sex-associated hormones such as estradiol, testosterone and progesterone have all been shown to modulate immune responses, which can result in differential disease outcomes between males and females, as well as between pregnant and nonpregnant females. Most parasitic diseases, including leishmaniasis, usually result in more severe disease in males compared with females. This review highlights our current knowledge concerning the role of sex hormones in modulating leishmaniasis in both clinical settings and experimental disease models.

Item type: Article
ID code: 12930
Keywords: leishmaniasis, sex-associated hormones, immune responses, biomedical sciences, pharmacology, Pharmacy and materia medica, Microbiology, Endocrine and Autonomic Systems, Immunology, Endocrinology, Neurology
Subjects: Medicine > Pharmacy and materia medica
Science > Microbiology
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Mr Scott Kilgariff
    Date Deposited: 21 Aug 2009 16:35
    Last modified: 04 Sep 2014 23:27
    URI: http://strathprints.strath.ac.uk/id/eprint/12930

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