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Open Access research that challenges the mind...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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A new drug vehicle - lipid coated biodegradable nanoparticles

Schäfer, J. and Sitterberg, Johannes and Ehrhardt, C. and Kumar, M.N.V. Ravi and Bakowsky, Udo (2008) A new drug vehicle - lipid coated biodegradable nanoparticles. Advances in Science and Technology, 57. pp. 148-153. ISSN 1662-8969

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Abstract

The preparation and charactersiation of novel lipid coated PLGA nanoparticles was investigated in the presented study. The size of the pure nanoparticles could be adjusted in dependence on the stabilizer content. The supported lipid bilayer surrounding the nanoparticles was formed by the liposome spreading technique. The Lipid- coated nanoparticles were characterised using Photon Correlation Spectroscopy (PCS) and atomic force microscopy (AFM) investigations. The bioadhesive properties was proofed in a cell culture model.