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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

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Pulsed UV-light in activation of poliovirus and adenovirus

Lamont, Y. and Rzeutka, A. and Anderson, J.G. and MacGregor, S.J. and Given, M.J. and Deppe, C. and Cook, N. (2007) Pulsed UV-light in activation of poliovirus and adenovirus. Letters in Applied Microbiology, 45 (5). pp. 564-567. ISSN 0266-8254

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Abstract

To study the pulsed ultraviolet (UV) inactivation of poliovirus and adenovirus. Viral suspensions of 2 ml volume were exposed to varying numbers of polychromatic light pulses emitted from a xenon flashlamp. Ten pulses produced an approximately 4 log10 reduction in poliovirus titre, and no infectious poliovirus remained after 25 pulses. With adenovirus, 10 pulses resulted in an approximately 1 log10 reduction in infectivity. Adenovirus required 100 pulses to produce an approximately 3 log10 reduction in infectivity, and 200 pulses to produce a greater than 4 log10 reduction. Adenovirus was more resistant to pulsed UV treatment than poliovirus although both viruses showed susceptibility to the treatment. Pulsed UV-light treatment proved successful in the inactivation of poliovirus and adenovirus, and represents an alternative to continuous-wave UV treatment.