Structural transformations in zopiclone

Shankland, N. and David, W.I.F. and Shankland, K. and Kennedy, A.R. and Frampton, C.S. and Florence, A.J. (2001) Structural transformations in zopiclone. Chemical Communications (London), 2001 (21). pp. 2204-2205. ISSN 0009-241X (http://dx.doi.org/10.1039/b107075d)

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Abstract

A monoclinic centrosymmetric form of zopiclone dihydrate undergoes a sequential, two-step transformation in the solid-state upon heating which results in separation of the enantiomers into a racemic conglomerate or racemic twins.