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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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1,4-pentadienyl-3-sulfonamides: Frameworks for disfavored radical cascade cyclizations

Bommezijn, Sacha and Martin, Concepcion Gonzalez and Kennedy, Alan R. and Lizos, Dimitrios and Murphy, John A. (2001) 1,4-pentadienyl-3-sulfonamides: Frameworks for disfavored radical cascade cyclizations. Organic Letters, 3 (21). pp. 3405-3407. ISSN 1523-7060

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Abstract

1,4-Pentadienyl-3-sulfonamides afford products including those resulting from disfavored 5-endo-trig reactions when subjected to radical cyclization conditions. Products resulting from pathways featuring 4-exo-trig cyclizations are also detected, even when the 4-exo-trig reaction leads to a highly strained bicyclo[3.2.0] ring system.