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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Surface-enhanced resonance Raman scattering in optical tweezers using co-axial second harmonic generation

Jordan, P. and Cooper, J. and McNay, G. and Docherty, F.T. and Graham, D. and Smith, W.E. and Sinclair, G. and Padgett, M.J. (2005) Surface-enhanced resonance Raman scattering in optical tweezers using co-axial second harmonic generation. Optics Express, 13 (11). pp. 4148-4153. ISSN 1094-4087

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Abstract

Silica particles were partially coated with silver, and a suitable chromophore, such that they could be trapped within an optical tweezers system and simultaneously be excited to emit a surface-enhanced resonance Raman scattering (SERRS) spectrum. A standard 1064 nm TEM00 mode laser was used to trap the bead whilst a frequency doubling crystal inserted into the beam gave several microwatts of 532 nm co-linear light to excite the SERRS emission. The configuration has clear applications in providing apparatus that can manipulate a particle whilst simultaneously obtaining surface sensitive sensory information.