Picture of scraped petri dish

Scrape below the surface of Strathprints...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Explore world class Open Access research by researchers at Strathclyde, a leading technological university.

Explore

DNA detection by surface enhanced resonance Raman scattering (SERRS)

Faulds, K. and Smith, W.E. and Graham, D. (2005) DNA detection by surface enhanced resonance Raman scattering (SERRS). Analyst, 130 (8). pp. 1125-1131. ISSN 0003-2654

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

This Education article outlines the different ways in which surface enhanced resonance Raman scattering (SERRS) can be used for the detection of DNA. The use of various different SERRS detection strategies that have allowed both sensitive and selective detection to be obtained is covered. Detection of DNA by SERRS involves the use of a dye with the DNA, whether as an intercalator or by direct covalent attachment. This generates strong SERRS signals that indicate the presence of the specific DNA sequence. The SERRS detection of DNA in different molecular biological assays is also discussed.