Paredes, R. and Abonia, R. and Cadavid, J. and Moreno-Fuquen, Rodolfo and Jaramillo, A. and Hormaza, A. and Ramirez, A. and Kennedy, A.R. (2001) A mechanistic study of the ammonolysis of alkyl acetoacetates in water. Formation of 1,5-dimethyl-2,6,9- triazabicyclo[3.3.1]nonane-3,7-dione as the main product. Tetrahedron, 58 (1). pp. 55-60. ISSN 0040-4020Full text not available in this repository. (Request a copy from the Strathclyde author)
Ammonolysis of alkyl acetoacetates with 15% NH3 in water at room temperature initially lead to formation of alkyl β-aminocrotonates which slowly converted into 1,5-dimethyl-2,6,9-triaza-bicyclo[3.3.1]nonane-3,7-dione as the main product.
|Keywords:||Ammonolysis, alkyl acetoacetates, temperature, aminocrotonates, Chemistry, Biochemistry, Organic Chemistry, Drug Discovery|
|Subjects:||Science > Chemistry|
|Department:||Faculty of Science > Pure and Applied Chemistry|
|Depositing user:||Catriona Mccallum|
|Date Deposited:||22 May 2006|
|Last modified:||22 Mar 2017 09:07|