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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence

Faulds, K. and Barbagallo, R.P. and Keer, J.T. and Smith, W.E. and Graham, D. (2004) SERRS as a more sensitive technique for the detection of labelled oligonucleotides compared to fluorescence. Analyst, 129 (7). pp. 567-568. ISSN 0003-2654

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Abstract

This communication contains data from a comparison between the detection limits obtained using surface enhanced resonance Raman scattering (SERRS) and fluorescence detection of dye labelled oligonucleotides. The results show that the detection limits for SERRS are generally at least three orders of magnitude lower than those obtained for fluorescence.