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Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides

Brown, R. and Smith, W.E. and Graham, D. (2003) Synthesis of a benzotriazole azo dye phosphoramidite for labelling of oligonucleotides. Tetrahedron Letters, 44 (7). pp. 1339-1342. ISSN 0040-4039

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Abstract

The synthesis of a benzotriazole azo dye phosphoramidite and the subsequent use in solid phase synthesis of oligonucleotides is reported. The azo dye is shown as a surface enhanced resonance Raman label for oligonucleotides that is capable of immobilisation of the oligonucleotide on metal surfaces such as silver nanoparticles. (C) 2003 Elsevier Science Ltd. All rights reserved.

Item type: Article
ID code: 1099
Keywords: resonance raman-scattering, nanoparticle probes, dna, serrs, Chemistry
Subjects: Science > Chemistry
Department: Faculty of Science > Pure and Applied Chemistry
Unknown Department
Related URLs:
Depositing user: Mr Derek Boyle
Date Deposited: 18 May 2006
Last modified: 12 Mar 2012 10:36
URI: http://strathprints.strath.ac.uk/id/eprint/1099

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