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Toxicity of codeine, codeinone and oxycodone in hep g2 cells: identification of a codeinone-glutathione conjugate by lC/+ECI-MS/MS

Jairaj, M. and Watson, D.G. and Grant, M.H. and Skellern, G.G. (2002) Toxicity of codeine, codeinone and oxycodone in hep g2 cells: identification of a codeinone-glutathione conjugate by lC/+ECI-MS/MS. In: 50th Meeting of the American Society for Mass Spectrometry, 2002-06-02 - 2002-06-06.

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Abstract

Development of new mass spectrometers and implementation of new analytical methods were the central themes of the conference. This paper focused on the toxicity of codeine, codeinone and oxycodone in hep g2 cells: identification of a codeinone-glutathione conjugate by lC/+ECI-MS/MS.