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Surface enhanced resonance Raman scattering (SERRS) - a first example of its use in multiplex genotyping

Graham, D. and Mallinder, B.J. and Whitcombe, D. and Smith, W.E. (2001) Surface enhanced resonance Raman scattering (SERRS) - a first example of its use in multiplex genotyping. ChemPhysChem, 2 (12). pp. 746-748. ISSN 1439-4235

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Abstract

Accurate multiplex genotyping of the mutational status of the cystic fibrosis gene with the sensitive and selective SERRS technique is reported. This new assay does not require separation of the various alleles and shows that SERRS is a realistic alternative detection technique for use in modern DNA assays.