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Cyclobutanes from Combretum albopunctatum

Katerere, D.R. and Gray, A.I. and Kennedy, A.R. and Nash, R.J. and Waigh, R.D. (2004) Cyclobutanes from Combretum albopunctatum. Phytochemistry, 65 (4). pp. 433-438. ISSN 0031-9422

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A dichloromethane extract of the aerial parts of Combretum albopunctatum Suessengafforded five phenolic compounds - three known flavonoids and two novel cyclobutane chalcone dimers. The chemical structures were determined by standard spectroscopic techniques and the structure and relative stereochemistry of one chalcone dimer, rel-(1a,2b)-di-(2,6-dimethoxy-4-hydroxy)-benzoylrel-(3a,4b)-diphenylcyclobutane, were confirmed by single crystal X-ray diffraction.